Southern Fried Python Nuggets
Expertly prepared python recipe

Southern Fried Python Nuggets

Python Recipe

1Setup & Prepare

About This Recipe

Tender python meat marinated in buttermilk, breaded with seasoned flour, and deep-fried until crispy—Florida's answer to chicken nuggets.

Cultural Context

(150 words) Deep-frying is the quintessential Southern cooking method, turning everything from chicken to catfish into crispy, golden perfection. When Florida python hunters began harvesting massive snakes from the Everglades, Southern chefs naturally gravitated toward frying as the best preparation method. The breading seals in moisture while creating textural contrast, and the quick, hot cooking prevents the meat from becoming rubbery. Python nuggets have become popular at wildlife festivals and hunting camps across Florida, served alongside traditional sides like coleslaw and hush puppies. This preparation honors Southern food traditions while addressing an environmental crisis—each plate of fried python represents one less invasive predator threatening native species. The dish bridges exotic eating with comfort food familiarity, making python accessible to adventurous eaters. It's conservation you can taste.

2Ingredients

Shopping List

21 ingredients total17 with images5 with substitutions

3Cooking Instructions

  1. Cut python meat into uniform 1-inch nuggets, removing any visible membrane or silver skin with sharp knife—this reduces chewiness significantly.
  2. Combine buttermilk, hot sauce, garlic powder, onion powder, cayenne, salt, and pepper in large bowl. Add python nuggets and turn to coat. Cover and refrigerate for minimum 4 hours or overnight—this tenderizes the meat and adds flavor.
  3. In large bowl, whisk together flour, cornmeal, Creole seasoning, garlic powder, paprika, cayenne, black pepper, and salt until well combined.
  4. Heat 3 inches of vegetable oil in deep Dutch oven or deep fryer to exactly 375°F. Use a thermometer—proper temperature is crucial.
  5. Working in batches, remove python nuggets from buttermilk, allowing excess to drip off. Dredge thoroughly in seasoned flour mixture, pressing coating into meat. Shake off excess.
  6. Carefully lower nuggets into hot oil, frying in small batches to maintain oil temperature. Fry for 3-4 minutes until deep golden brown and crispy, turning once. Internal temperature should reach 165°F.
  7. Remove with spider or slotted spoon to paper towel-lined plate. Season immediately with salt while hot. Rest for 2 minutes before serving to allow carry-over cooking.
  8. Serve hot with lemon wedges, remoulade sauce, and traditional Southern sides like coleslaw, mac and cheese, and collard greens.

4Chef's Notes & Pairings

Chef's Notes

  • Removing the membrane is essential—it makes python much less chewy and more tender.
  • Don't skip the buttermilk marinade; it's the key to tender python nuggets.
  • Maintain oil temperature at 375°F—too cool and the coating absorbs grease; too hot and it burns before meat cooks.
  • Python must reach 165°F internal temperature for food safety.
  • The cornmeal addition creates extra-crispy texture that stays crunchy longer.

Wine Pairing

Dry Riesling or Cold Beer – A crisp German Riesling cuts through the fried coating, but ice-cold beer is the traditional Southern choice.

Nutrition Facts

(per serving) Calories: 385 | Protein: 42g | Fat: 18g | Carbohydrates: 22g | Iron: 3.2mg

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